000			04002cam a22004698i 4500
001			22877526
003			OSt
005			20250830120641.0
008			221125s2023 nju b 001 0 eng
010			_a 2022053778
020			_a9781119437970 _q(Paperback)
020			_z9781119437963 _q(ePDF)
020			_z9781119437840 _q(ePUB)
035			_a22877526
040			_aDLC _beng _erda _cTUPM
042			_apcc
050			_aQD 415 _bM55 2024
100	1		_aMiller, Andrew, _d1963- _eauthor.
245	1	0	_aEssentials of chemical biology : _bstructures and dynamics of biological macromolecules in vitro and in vivo / _cAndrew D. Miller, Department of Chemistry, Imperial College London, UK, Julian A. Tanner, Department of Biochemistry, University of Hong Kong.
250			_aSecond edition.
263			_a2304
264		1	_aHoboken, New Jersey : _bJohn Wiley & Sons Inc., _c[2024]
300			_axvii, 537 pages : _billustrations (chiefly color) ; _c25 cm.
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
504			_aIncludes bibliographical references and index.
505			_aThe structures of biological macromolecules and lipid assemblies Chemical and biological synthesis Molecular biology as a toolset for chemical biology Electronic and vibrational spectroscopy Magnetic resonance Diffraction and microscopy Molecular recognition and binding Kinetics and catalysis Mass spectrometry and proteomics Molecular selection and evolution Chemical biology of cells Chemical biology of stem cells to tissue engineering Chemical biology, nanomedicine and advanced therapeutics Chemical biology and advanced diagnostics leading to precision therapeutic approaches DNA nanotechnology
520			_a"Since the first edition of this Textbook, Chemical Biology has now established itself as a major branch of scientific activity devoted to understanding the way Biology works at the molecular level. Chemical Biology itself remains unashamedly multidisciplinary, and Chemical Biology research is essentially problem driven and not discipline driven. Organic, Physical, Inorganic and Analytical Chemistry all contribute towards Chemical Biology alongside newer emerging molecular disciplines. Some might say that Chemical Biology is just another way to rebadge Biochemistry. However, such a comment misses the point. Biochemistry may have started as a discipline devoted to the study of individual biological macromolecules, but this discipline has been steadily evolving into increasingly descriptive, empirical studies of larger and larger macromolecular assemblies, structures and interacting molecular networks. The molecular increasingly gives ground to the cellular. In contrast, Chemical Biology is about Chemistry trained graduates and researchers taking a fundamental interest in the way Biology works. Consequently, the focus is on the molecular and the quantitative where molecular properties are investigated, studied and then gradually linked to macromolecular and cellular behaviour where possible. This is a fundamentally bottom-up approach to understanding Biology in keeping with the chemist's natural enthusiasm and appreciation for molecular structure and behaviour first and foremost"-- _cProvided by publisher.
590			_aMiller, A., & Tanner, J. (2024). Essentials of chemical biology: Structures and dynamics of biological macromolecules in vitro and in vivo (2nd ed.). John Wiley & Sons Inc.
650		0	_aBiochemistry.
650		0	_aMolecular biology.
650		0	_aMacromolecules.
650		0	_aChemical biology.
650		0	_aBiomolecules _xStructure.
650		0	_aMacromolecules _xPhysiology.
700	1		_aTanner, Julian, _d1976- _eauthor.
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2lcc _cBK _n0
999			_c30690 _d30690